At TRIA, we balance measuring patient outcomes, which can be considered small continuous improvements, with innovative research studies, which are those grand advancements in orthopedic care. These research studies explore the latest in medical devices, instruments, implants, methods and procedures.

The Federal Government has finalized Section 1557 clarifying the nondiscrimination provision of the Affordable Care Act.  This Final Rule clarifies and codifies existing nondiscrimination requirements.  As part of this Final Rule, we have linked here for you our statement of nondiscrimination.

If you are interested in participating in one of our currently enrolling studies or would like more information, please contact the TRIA Research Institute: | 952-806-5603

Study Name:

A Randomized Comparison of NeoCart® to Microfracture for the Repair of Articular Cartilage Injuries in the Knee

Enrollment Status:

Current Study

Principal Investigator(s):

Brad Nelson, MD


Jeffrey Macalena, MD

Diagnosis Being Studied:

In the knee joints, the ends of bones are covered in a firm and durable tissue called articular cartilage. This tissue allows the bones to move smoothly over one another, promoting painless mobility for the knee joints.  Cartilage can become damaged from athletics, traumatic injury and normal wear and tear. Unfortunately, damaged cartilage has a limited ability to repair or restore itself. If left untreated, it might worsen and lead to chronic conditions.


NeoCart ® is an investigational cartilage tissue implant used to treat certain knee cartilage injuries. The procedure uses regenerative medicine technology to create tissue that acts like natural cartilage from a patient’s own cells.

Who Should Participate:

  • Male and females ages 18-55 years
  • Patients with one or two articular cartilage lesion(s) in the knee that require surgical treatment
  • Patients in good general health